Hemophilia is a rare genetic disorder that affects the blood’s ability to clot properly, leading to prolonged bleeding and potential complications. While there is no cure for hemophilia, various treatments can help manage the condition and prevent bleeding episodes. These treatments include replacement therapies with clotting factor concentrates, medications to control bleeding and promote clotting, and physical therapy to improve joint health. Read on to understand different treatment methods that can be used to treat hemophilia effectively.
Replacement Therapy
Replacement therapy is one of the most popular treatments for hemophilia. In this, clotting factor concentrates are slowly injected into a vein. These infusions help compensate for the clotting factor that’s missing or low. Some patients use replacement therapy regularly to prevent bleeding. This is referred to as preventive or prophylactic therapy. Others may use replacement therapy only when bleeding occurs — this is called demand therapy.
There are certain complications that might arise from replacement therapy:
- One may develop antibodies that attack the clotting factor.
- Human clotting factors could lead to viral infections.
- Delays in treatment may cause damage to muscles, joints, or other body parts.
Desmopressin (DDAVP)
Desmopressin is an artificial hormone for treating mild hemophilia A. DDAVP is usually given as a nasal spray or by injection. However, DDAVP is only given in certain situations. If used too frequently, the effect of this hormone wears off. For example, one might take this before dental procedures to reduce or prevent bleeding.
Antifibrinolytic Medicines
Antifibrinolytic medicines are usually given as a pill. They prevent blood clots from breaking down. They may be used with replacement therapy. These medications are typically taken before dental work to prevent moderate intestinal bleeding and bleeding from the nose or mouth.
Gene Therapy
Gene therapy is not accepted as a treatment for hemophilia. However, many researchers continue to explore ways to correct the faulty genes that cause this disease.
How to Find the Best Treatment?
The ideal hemophilia treatment should be selected based on the following factors:
- The severity of a person’s hemophilia.
- The activities they will be participating in.
- The dental and medical procedures they might need to have.
Usually, replacement therapy is given to people who have moderate or severe hemophilia. DDAVP is a good option for those with mild hemophilia.
